The main flight option for the route Shymkent – Dushanbe (round-trip) involves a layover. Prices start at 5 161SM.
The lowest prices for flights with layovers are offered by Air Astana with a layover in Almaty. Tickets start at 1 678SM.
Aviasales.tj suggests buying tickets from Shymkent Dushanbe in advance in order to choose the conditions for your flight that best suit your preferences and budget.